Saikosaponin D exhibits anti-leukemic activity by targeting FTO/m(6)A signaling

Sun, KJ; Du, YY; Hou, YZ; Zhao, MY; Li, JJ; Du, YZ; Zhang, LX; Chen, CB; Yang, HM; Yan, F; Su, R

Su, R (corresponding author), Changchun Univ Chinese Med, Jilin Ginseng Acad, Changchun 130017, Peoples R China.; Yan, F (corresponding author), Jilin Univ, State Key Lab Inorgan Synth & Preparat Chem, Int Joint Res Lab Nanomicro Architecture Chem NMA, Int Res Ctr Chem Med Joint Innovat,Coll Chem, 2699 Qianjin St, Changchun 130012, Peoples R China.

THERANOSTICS, 2021; 11 (12): 5831

Abstract

Purpose: The implementation of targeted therapies for acute myeloid leukemia (AML) has been challenging. Fat mass and obesity associated protein (FTO)......

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