The NRF2-p97-NRF2 negative feedback loop

Shakya, A; Liu, PF; Godek, J; Mckee, NW; Dodson, M; Anandhan, A; Ooi, A; Garcia, JGN; Costa, M; Chapman, E; Zhang, DD

Chapman, E; Zhang, DD (通讯作者)，Univ Arizona, Coll Pharm, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA.

REDOX BIOLOGY, 2023; 65 ():

Abstract

p97 is a ubiquitin-targeted ATP-dependent segregase that regulates proteostasis, in addition to a variety of other cellular functions. Previously, we ......

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