Aurka loss in CD19(+) B cells promotes megakaryocytopoiesis via IL-6/STAT3 signaling-mediated thrombopoietin production

Chen, X; Wang, CN; Sun, N; Pan, S; Li, RQ; Li, XQ; Zhao, J; Tong, H; Tang, YY; Han, J; Qiao, JL; Qiu, HB; Wang, H; Yang, J; Ikezoe, T

Wang, H; Yang, J (corresponding author), Xuzhou Med Univ, Dept Pathogen Biol & Immunol, Jiangsu Prov Key Lab Immun & Metab, 209 Tongshan Rd, Xuzhou 221004, Jiangsu, Peoples R China.

THERANOSTICS, 2021; 11 (10): 4655

Abstract

Rationale: Aurora kinase A (Aurora-A), which is required for mitosis, is a therapeutic target in various tumors. Targeting Aurora-A led to an increase......

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