Cellular cholesterol loss by DHCR24 knockdown leads to Aβ production by changing APP intracellular localization

Huang, Y; Zhang, WB; Guo, XR; Zhang, Y; Wu, JF; Zu, HB

Wu, JF; Zu, HB (通讯作者)，Fudan Univ, Dept Neurol, Jinshan Hosp, Shanghai, Peoples R China.

JOURNAL OF LIPID RESEARCH, 2023; 64 (5):

Abstract

For the past 20 years, the majority of cell culture studies reported that increasing cholesterol level increases amyloid-beta (A beta) production. Con......

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