Molecular basis for anti-insomnia drug design from structure of lemborexant-bound orexin 2 receptor

Asada, H; Im, D; Hotta, Y; Yasuda, S; Murata, T; Suno, R; Iwata, S

Asada, H; Iwata, S (通讯作者)，Kyoto Univ, Grad Sch Med, Dept Cell Biol, Kyoto 6068501, Japan.

STRUCTURE, 2022; 30 (12): 1582

Abstract

Orexin receptors are a family of G protein-coupled receptors that consist of two subtypes: orexin-1 receptors (OX1Rs) and OX2Rs. They are expressed th......

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