Synthesis and Evaluation of a QS-17/18-Based Vaccine Adjuvant

Wang, PF; Skalamera, D; Sui, XW; Zhang, P; Michalek, SM

Wang, PF (reprint author), Univ Alabama Birmingham, Dept Chem, 901 14th St South, Birmingham, AL 35294 USA.; Zhang, P (reprint author), Univ Alabama Birmingham, Dept Pediat Dent, 901 14th St South, Birmingham, AL 35294 USA.

JOURNAL OF MEDICINAL CHEMISTRY, 2019; 62 (3): 1669

Abstract

We have synthesized a QS-17/18 analogue (7) and evaluated its adjuvant activity in the formulation with rHagB antigen. Compound 7 and QS-21 analogues ......

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