ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination

Ren, GM; Zhang, XY; Xiao, Y; Zhang, W; Wang, Y; Ma, WB; Wang, XH; Song, P; Lai, LL; Chen, H; Zhan, YQ; Zhang, JH; Yu, M; Ge, CH; Li, CY; Yin, RH; Yang, XM

Yin, RH; Yang, XM (reprint author), Beijing Inst Life, Natl Ctr Prot Sci Beijing, Beijing Proteome Res Ctr, State Key Lab Prote, Beijing, Peoples R China.; Yang, XM (reprint author), Tianjin Univ, Sch Chem Engn & Technol, Dept Pharmaceut Engn, Tianjin, Pe

EMBO JOURNAL, 2019; 38 (6):

Abstract

Deubiquitination of NLRP3 has been suggested to contribute to inflammasome activation, but the roles and molecular mechanisms are still unclear. We he......

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