Whole-genome sequencing reveals a complex African population demographic history and signatures of local adaptation

Fan, SH; Spence, JP; Feng, YQ; Hansen, MEB; Terhorst, J; Beltrame, MH; Ranciaro, A; Hirbo, J; Beggs, W; Thomas, N; Nyambo, T; Mpoloka, SW; Mokone, GG; Njamnshi, A; Folkunang, C; Meskel, DW; Belay, G; Song, YS; Tishkoff, SA

Tishkoff, SA (通讯作者)，Univ Penn, Dept Genet, Philadelphia, PA 19104 USA.;Tishkoff, SA (通讯作者)，Univ Penn, Dept Biol, Philadelphia, PA 19104 USA.

CELL, 2023; 186 (5): 923

Abstract

We conduct high coverage (>303) whole-genome sequencing of 180 individuals from 12 indigenous African populations. We identify millions of unreport......

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