Efficiency and Safety of Dextran-PAMAM/siMMP-9 Complexes for Decreasing Matrix Metalloproteinase-9 Expression and Promoting Wound Healing in Diabetic Rats

Luo, HC; Mai, KJ; Liu, E; Chen, H; Xie, YJ; Zheng, YX; Lin, R; Zhang, LM; Zhang, Y

Zhang, Y (通讯作者),Guangzhou Med Univ, Dept Endocrinol, Affiliated Hosp 3, Guangzhou 510150, Peoples R China.;Zhang, LM (通讯作者),Sun Yat Sen Univ, Sch Mat Sci & Engn, DSAPM Lab, Guangzhou 510275, Peoples R China.;Zhang, LM (通讯作者),Sun Yat Sen Univ, Sch Mat Sci & Engn, PCFM Lab, Guangzhou 510275, Peoples R China.

BIOCONJUGATE CHEMISTRY, 2022; 33 (12): 2398

Abstract

Difficult healing of diabetic foot ulcers is associated with overexpression of matrix metalloproteinase 9 (MMP-9) in the local wound. Therefore, strat......

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