Thalidomide and Its Analogs Differentially Target Fibroblast Growth Factor Receptors: Thalidomide Suppresses FGFR Gene Expression while Pomalidomide Dampens FGFR2 Activity

Sundaresan, L; Kumar, P; Manivannan, J; Balaguru, UM; Kasiviswanathan, D; Veeriah, V; Anishetty, S; Chatterjee, S

Chatterjee, S (reprint author), Anna Univ, AU KBC Res Ctr, Chennai 600044, Tamil Nadu, India.; Chatterjee, S (reprint author), Anna Univ, Dept Biotechnol, Chennai 600044, Tamil Nadu, India.

CHEMICAL RESEARCH IN TOXICOLOGY, 2019; 32 (4): 589

Abstract

Thalidomide is an infamous teratogen and it is continuously being explored for its anticancer properties. Fibroblast growth factor receptors (FGFRs) a......

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