A germline HLTF mutation in familial MDS induces DNA damage accumulation through impaired PCNA polyubiquitination

Takaoka, K; Kawazu, M; Koya, J; Yoshimi, A; Masamoto, Y; Maki, H; Toya, T; Kobayashi, T; Nannya, Y; Arai, S; Ueno, T; Ueno, H; Suzuki, K; Harada, H; Manabe, A; Hayashi, Y; Mano, H; Kurokawa, M

Kurokawa, M (reprint author), Univ Tokyo, Dept Hematol & Oncol, Tokyo, Japan.

LEUKEMIA, 2019; 33 (7): 1773

Abstract

Although several causal genes of familial myelodysplastic syndromes (MDS) have been identified, the genetic landscape and the molecular pathogenesis a......

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