Cascade Wolff Rearrangement and Double N-Acylation: A Cyclization of a-Diazoketones with 2-aminopyridines or 3-aminopyrazoles to Synthesize Fused Pyrimidinediones

Ren, JJ; Zhou, JX; Song, YQ; Zhang, AX; Zhao, LX; Zhao, ZY; Zhu, YP; Zhu, W

Zhu, YP; Zhu, W (通讯作者)，Yantai Univ, Collaborat Innovat Ctr Adv Drug Delivery Syst & Bi, Minist Educ, Sch Pharm,Key Lab Mol Pharmacol & Drug Evaluat, Yantai 264005, Shandong, Peoples R China.;Zhu, YP (通讯作者)，Anhui Normal Univ, Coll Chem & Mat Sci, Anhui Key Lab Mol Based Mat, Wuhu 241000, Peoples R China.

ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (23): 4121

Abstract

A cascade Wolff rearrangement and double N-acylation reaction has been developed for the synthesis of fused pyrimidinediones in one-pot under air. The......

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