Estimation of the binomial probabilities in a two-stage phase II clinical trial with two co-primary endpoints

Sun, YM; Zhang, XY; Tan, XM; Tu, DS

Tu, DS (corresponding author), Queens Univ, Canadian Canc Trials Grp, Kingston, ON K7L 3N6, Canada.

CONTEMPORARY CLINICAL TRIALS, 2021; 105 ():

Abstract

In cancer research, two-stage designs are usually used to assess the effect of a new agent in phase II clinical trials. Optimal two-stage designs with......

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