Forced Intercalation (FIT)-Aptamers

Ebrahimi, SB; Samanta, D; Cheng, HF; Nathan, LI; Mirkin, CA

Mirkin, CA (reprint author), Northwestern Univ, Dept Chem & Biol Engn, Evanston, IL 60208 USA.; Mirkin, CA (reprint author), Northwestern Univ, Dept Chem, 2145 Sheridan Rd, Evanston, IL 60208 USA.; Mirkin, CA (reprint author), Northwestern Univ, Int Inst

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2019; 141 (35): 13744

Abstract

Aptamers are oligonucleotide sequences that can be evolved to bind to various analytes of interest. Here, we present a general design strategy that tr......

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