CRISPR-mediated rapid generation of neural cell-specific knockout mice facilitates research in neurophysiology and pathology

Xiao, D; Zhang, WF; Wang, Q; Li, X; Zhang, Y; Rasouli, J; Casella, G; Ciric, B; Curtis, M; Rostami, A; Zhang, GX

Zhang, GX (corresponding author), Thomas Jefferson Univ, Dept Neurol, JHN 300, Philadelphia, PA 19107 USA.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 (): 755

Abstract

Inducible conditional knockout mice are important tools for studying gene function and disease therapy, but their generation is costly and time-consum......

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