HBV pre-core mutant in genotype-D infected children is selected during HBeAg/anti-HBe seroconversion and leads to HBeAg negative chronic hepatitis B in adulthood

Colombatto, P; Barbera, C; Bortolotti, F; Maina, AM; Moriconi, F; Cavallone, D; Calvo, P; Oliveri, F; Bonino, F; Brunetto, MR

Brunetto, MR (reprint author), Univ Hosp Pisa, Hepatol Unit, Via Paradisa 2 Cisanello, I-56124 Pisa, Italy.; Brunetto, MR (reprint author), Univ Pisa, Dept Clin & Expt Med, Internal Med, Via Paradisa 2 Cisanello, I-56124 Pisa, Italy.

JOURNAL OF MEDICAL VIROLOGY, 2018; 90 (7): 1232

Abstract

Selection of HBeAg defective HBV mutants (mt) during childhood might influence infection outcome in adults. Aim of this study was to correlate the dyn......

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