Structural basis for histone variant H3tK27me3 recognition by PHF1 and PHF19

Dong, C; Nakagawa, R; Oyama, K; Yamamoto, Y; Zhang, WL; Dong, AP; Li, YJ; Yoshimura, Y; Kamiya, H; Nakayama, J; Ueda, J; Min, JR

Min, JR (corresponding author), Univ Toronto, Struct Genom Consortium, Toronto, ON, Canada.; Min, JR (corresponding author), Univ Toronto, Dept Physiol, Toronto, ON, Canada.

ELIFE, 2020; 9 ():

Abstract

The Polycomb repressive complex 2 (PRC2) is a multicomponent histone H3K27 methyltransferase complex, best known for silencing the Hox genes during em......

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