Discovery of N-aryl sulphonamide-quinazoline derivatives as anti-gastric cancer agents in vitro and in vivo via activating the Hippo signalling pathway

Niu, JB; Hua, CQ; Liu, Y; Yu, GX; Yang, JJ; Li, YR; Zhang, YB; Qi, YQ; Song, J; Jin, CY; Zhang, SY

Niu, JB; Jin, CY; Zhang, SY (corresponding author), Zhengzhou Univ, Affiliated Hosp 3, Zhengzhou 450001, Peoples R China.; Song, J (corresponding author), Zhengzhou Univ, Sch Pharmaceut Sci, Inst Drug Discovery & Dev, Key Lab Adv Drug Preparat Technol,Minist Educ, Zhengzhou 450001, Peoples R China.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2021; 36 (1): 1715

Abstract

Hippo signalling pathway plays a crucial role in tumorigenesis and cancer progression. In this work, we identified an N-aryl sulphonamide-quinazoline ......

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