Integrated population pharmacokinetics of etirinotecan pegol and its four metabolites in cancer patients with solid tumors

Sy, SKB; Chia, YL; Gordi, T; Hoch, U; Eldon, MA

Eldon, MA (reprint author), Nektar Therapeut, Dept Clin Pharmacol, 455 Mission Bay Blvd South, San Francisco, CA 94158 USA.

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018; 81 (5): 897

Abstract

Etirinotecan pegol (EP), a long-acting topoisomerase-1 inhibitor, is a polyethylene glycol conjugate of irinotecan, with an intended indication for tr......

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