Multiparameter Flow Cytometry Assay for Quantification of Immune Cell Subsets, PD-1 Expression Levels and PD-1 Receptor Occupancy by Nivolumab and Pembrolizumab

Pluim, D; Ros, W; Miedema, IHC; Beijnen, JH; Schellens, JHM

Pluim, D (reprint author), Netherlands Canc Inst Antoni van Leeuwenhoek NKI, Div Pharmacol, Amsterdam, Netherlands.

CYTOMETRY PART A, 2019; 95 (10): 1053

Abstract

We report the development and validation of a 12 parameter immunofluorescence flow cytometry method for the sensitive determination of cell concentrat......

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