Synthesis of Lathyrol PROTACs and Evaluation of Their Anti- Inflammatory Activities

Wang, W; Liu, Y; Xiong, LL; Sun, DJ; Wang, H; Song, ZR; Li, YT; Li, H; Chen, LX

Li, H; Chen, LX (通讯作者)，Fujian Univ Tradit Chinese Med, Inst Struct Pharmacol & TCM Chem Biol, Coll Pharm, Fuzhou 350122, Peoples R China.;Li, H; Chen, LX (通讯作者)，Shenyang Pharmaceut Univ, Wuya Coll Innovat, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang 110016, Peoples R China.

JOURNAL OF NATURAL PRODUCTS, 2023; 86 (4): 767

Abstract

Lathyrol is a core scaffold structure of many lathyrane diterpenoids with potent anti-inflammatory activity isolated from Euphorbia lathyrism. It was ......

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