Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer's disease

Chen, JF; Liu, K; Hu, B; Li, RR; Xin, W; Chen, H; Wang, F; Chen, L; Li, RX; Ren, SY; Xiao, L; Chan, JR; Mei, F

Xiao, L; Mei, F (corresponding author), Third Mil Med Univ, Dept Histol & Embryol, Brain & Intelligence Res Key Lab, Chongqing Educ Commiss, Chongqing 400038, Peoples R China.; Chan, JR (corresponding author), Univ Calif San Francisco, Dept Neurol, UCSF Weill Inst Neurosci, San Francisco, CA 94158 USA.

NEURON, 2021; 109 (14): 2292

Abstract

Severe cognitive decline is a hallmark of Alzheimer's disease (AD). In addition to gray matter loss, significant white matter pathology has been ident......

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