Thioether Macrocyclic Peptides Selected against TET1 Compact Catalytic Domain Inhibit TET1 Catalytic Activity

Nishio, K; Belle, R; Katoh, T; Kawamura, A; Sengoku, T; Hanada, K; Ohsawa, N; Shirouzu, M; Yokoyama, S; Suga, H

Suga, H (reprint author), Univ Tokyo, Dept Chem, Grad Sch Sci, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan.

CHEMBIOCHEM, 2018; 19 (9): 979

Abstract

The ten-eleven translocation (TET) protein family, consisting of three isoforms (TET1/2/3), have been found in mammalian cells and have a crucial role......

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