A novel intestinal-restricted FXR agonist

Wang, H; Zhao, Z; Zhou, JY; Guo, YT; Wang, GJ; Hao, HP; Xu, XW

Hao, HP; Xu, XW (reprint author), China Pharmaceut Univ, State Key Lab Nat Med, Tongjiaxiang 24, Nanjing 210009, Jiangsu, Peoples R China.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017; 27 (15): 3386

Abstract

In this study, a new intestinal-restricted FXR agonist named fexaramine-3 (Fex-3) was developed and investigated both in vitro and in vivo. Fex-3 coul......

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