DDAH2 suppresses RLR-MAVS-mediated innate antiviral immunity by stimulating nitric oxide-activated, Drp1-induced mitochondrial fission

Huang, S; Li, ZX; Wu, ZW; Liu, C; Yu, MH; Wen, MJ; Zhang, LY; Wang, X

Wang, X (corresponding author), Capital Med Univ, Sch Basic Med Sci, Dept Immunol, Beijing 100069, Peoples R China.; Wang, X (corresponding author), Capital Med Univ, Adv Innovat Ctr Human Brain Protect, Beijing Key Lab Canc Invas & Metastasis, Dept Oncol, Beijing 100069, Peoples R China.; Wang, X (corresponding author), Tianjin Med Univ, Sch Basic Med Sci, Dept Cell Biol, Tianjin 300070, Peoples R China.; Zhang, LY; Wang, X (corresponding author), Shanxi Med Univ, Shanxi Bethune Hosp, Shanxi Ac

SCIENCE SIGNALING, 2021; 14 (678):

Abstract

The RIG-I-like receptor (RLR) signaling pathway is pivotal for innate immunity against invading viruses, and dysregulation of this molecular cascade h......

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