Cell surface dynamics and cellular distribution of endogenous FcRn

D'Hooghe, L; Chalmers, AD; Heywood, S; Whitley, P

Heywood, S (reprint author), UCB Pharma Ltd, Slough, Berks, England.; Whitley, P (reprint author), Univ Bath, Dept Biol & Biochem, Bath, Avon, England.

PLOS ONE, 2017; 12 (8):

Abstract

A major role for FcRn is the salvage of pinocytosed IgG and albumin from a degradative fate in lysosomes. FcRn achieves this by binding IgG in a pH-de......

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