Adriamycin induces cardiac fibrosis in mice via PRMT5-mediated cardiac fibroblast activation

Dong, XL; Yuan, BH; Yu, SZ; Liu, H; Pan, XH; Sun, J; Pan, LL

Pan, LL (通讯作者)，Jiangnan Univ, Wuxi Sch Med, Wuxi 214122, Jiangsu, Peoples R China.;Sun, J (通讯作者)，Jiangnan Univ, Sch Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China.;Sun, J (通讯作者)，Jiangnan Univ, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2023; 44 (3): 573

Abstract

Long-term treatment with adriamycin (ADR) is associated with higher incidences of cumulative cardiotoxicity manifest as heart failure. ADR-induced car......

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