Recovery from spindle checkpoint-mediated arrest requires a novel Dnt1-dependent APC/C activation mechanism

Bai, S; Sun, L; Wang, X; Wang, SM; Luo, ZQ; Wang, YM; Jin, QW

Luo, ZQ; Wang, YM; Jin, QW (通讯作者),Xiamen Univ, Fac Med & Life Sci, Sch Life Sci, State Key Lab Cellular Stress Biol, Xiamen, Fujian, Peoples R China.

PLOS GENETICS, 2022; 18 (9):

Abstract

The activated spindle assembly checkpoint (SAC) potently inhibits the anaphase-promoting complex/cyclosome (APC/C) to ensure accurate chromosome segre......

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