BH3 mimetics potentiate pro-apoptotic activity of encorafenib in BRAF(V600E) melanoma cells

Hartman, ML; Gajos-Michniewicz, A; Talaj, JA; Mielczarek-Lewandowska, A; Czyz, M

Hartman, ML (corresponding author), Med Univ Lodz, Dept Mol Biol Canc, 6-8 Mazowiecka St, PL-92215 Lodz, Poland.

CANCER LETTERS, 2021; 499 (): 122

Abstract

BRAF(V600)- and MEK1/2-targeting therapies rarely produce durable response in melanoma patients. We investigated five BRAF(V600E) melanoma cell lines ......

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