A newly developed PLD1 inhibitor ameliorates rheumatoid arthritis by regulating pathogenic T and B cells and inhibiting osteoclast differentiation

Park, JS; Yang, S; Song, D; Kim, SM; Choi, J; Kang, HY; Jeong, HY; Han, G; Min, DS; Cho, ML; Park, SH

Cho, ML; Park, SH (通讯作者)，Catholic Univ Korea, Catholic Res Inst Med Sci, Rheumatism Res Ctr, 222 Banpo Daero, Seoul 06591, South Korea.;Park, SH (通讯作者)，Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Internal Med,Div Rheumatol, 222 Banpo Daero, Seoul 06591, South Korea.;Min, DS (通讯作者)，Yonsei Univ, Coll Pharm, 85 Songdogwahak Ro, Incheon 21983, South Korea.

IMMUNOLOGY LETTERS, 2023; 263 (): 87

Abstract

Phospholipase D1 (PLD1), which catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline, plays multiple roles in inflammation.......

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