The Major Orphan Forms of Ichthyosis Are Characterized by Systemic T-Cell Activation and Th-17/Tc-17/Th-22/Tc-22 Polarization in Blood

Czarnowicki, T; He, H; Leonard, A; Malik, K; Magidi, S; Rangel, S; Patel, K; Ramsey, K; Murphrey, M; Song, T; Estrada, Y; Wen, HC; Krueger, JG; Guttman-Yassky, E; Paller, AS

Paller, AS (reprint author), Northwestern Univ, Feinberg Sch Med, Dept Dermatol, 676 N St Clair,Suite 1600, Chicago, IL 60611 USA.

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2018; 138 (10): 2157

Abstract

The ichthyoses are rare skin disorders with immune and barrier aberrations. Identifying blood phenotypes may advance targeted therapeutics. We aimed t......

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