Similarity demonstrated between isolated charge variants of MB02, a biosimilar of bevacizumab, and Avastin (R) following extended physicochemical and functional characterization

Ruppen, I; Beydon, ME; Solis, C; Sacristan, D; Vandenheede, I; Ortiz, A; Sandra, K; Adhikary, L

Ruppen, I (通讯作者),C Manuel Pombo Angulo 28,4th Floor, Madrid 28050, Spain.

BIOLOGICALS, 2022; 77 (): 1

Abstract

The majority of recombinant mAb products contain heterogeneous charge variants, commonly the result of post-translational modifications occurring duri......

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