MARCH5-dependent NLRP3 ubiquitination is required for mitochondrial NLRP3-NEK7 complex formation and NLRP3 inflammasome activation

Park, YJ; Dodantenna, N; Kim, Y; Kim, TH; Lee, HS; Yoo, YS; Heo, J; Lee, JH; Kwon, MH; Kang, HC; Lee, JS; Cho, H

Cho, H (通讯作者)，Ajou Univ, Dept Biochem, Sch Med, Suwon, South Korea.;Lee, JS (通讯作者)，Chungnam Natl Univ, Coll Vet Med, Daejeon, South Korea.

EMBO JOURNAL, 2023; 42 (19):

Abstract

The NLRP3 inflammasome plays a key role in responding to pathogens, and endogenous damage and mitochondria are intensively involved in inflammasome ac......

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