Disrupted hypothalamicCRHneuron responsiveness contributes to diet-induced obesity

Zhu, CJ; Xu, YZ; Jiang, ZY; Tian, JB; Cassidy, RM; Cai, ZL; Shu, G; Xu, Y; Xue, MS; Arenkiel, BR; Jiang, QY; Tong, QC

Jiang, QY (corresponding author), South China Agr Univ, Guangdong Prov Key Lab Anim Nutr Regulat, Guangdong Lab Lingnan Modern Agr, Coll Anim Sci, Guangzhou, Peoples R China.; Jiang, QY (corresponding author), South China Agr Univ, Natl Engn Res Ctr Breeding Swine Ind, Coll Anim Sci, Guangzhou, Peoples R China.; Tong, QC (corresponding author), Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Brown Fdn Inst Mol Med, Houston, TX 77030 USA.; Tong, QC (corresponding author), Univ Texas Hlth Sci Ctr Houston, Grad Program Neurosci, MD Anderson Canc Ctr UTHlth, Grad Sch Biomed Sci, Houston, TX 77030 USA.; Tong, QC (corresponding author), Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Neurobiol & Anat, Houston, TX 77030 USA.

EMBO REPORTS, 2020; 21 (7):

Abstract

The current obesity epidemic mainly results from high-fat high-caloric diet (HFD) feeding and may also be contributed by chronic stress; however, the ......

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