Synthesis and structure-activity relationship studies of 1,5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 1 (JAK1) inhibitors

Kim, W; Lee, SM; Jeong, PH; Jung, JH; Kim, YC

Kim, YC (通讯作者),Gwangju Inst Sci & Technol GIST, Sch Life Sci, Gwangju 61005, South Korea.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022; 55 ():

Abstract

JAK inhibitors have been considered as useful targets for the treatment of related diseases. However, firstgeneration JAK inhibitors have side effects......

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