A Cell Assay for Detecting Anti-PEG Immune Response against PEG-Modified Therapeutics

Shimizu, T; Abu Lila, AS; Awata, M; Kubo, Y; Mima, Y; Hashimoto, Y; Ando, H; Okuhira, K; Ishima, Y; Ishida, T

Ishida, T (reprint author), Tokushima Univ, Inst Biomed Sci, Dept Pharmacokinet & Biopharmaceut, 1-78-1 Sho Machi, Tokushima 7708505, Japan.

PHARMACEUTICAL RESEARCH, 2018; 35 (11):

Abstract

Purpose Immunogenicity of PEGylated proteins and nanomedicines represents a potential impediment against their development and use in clinical setting......

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