Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer

Means, AL; Freeman, TJ; Zhu, J; Woodbury, LG; Marincola-Smith, P; Wu, C; Meyer, AR; Weaver, CJ; Padmanabhan, C; An, HB; Zi, JH; Wessinger, BC; Chaturvedi, R; Brown, TD; Deane, NG; Coffey, RJ; Wilson, KT; Smith, JJ; Sawyers, CL; Goldenring, JR; Novits

Beauchamp, RD (reprint author), Vanderbilt Univ, Med Ctr, Med Ctr North, 1161 21st Ave South,D-4316, Nashville, TN 37232 USA.; Means, AL (reprint author), Vanderbilt Univ, Med Ctr, Med Ctr North, 1161 21st Ave South,D-2300, Nashville, TN 37232 USA.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2018; 6 (3): 257

Abstract

BACKGROUND & AIMS: Chronic inflammation is a predisposing condition for colorectal cancer. Many studies to date have focused on proinflammatory si......

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