1,2,4-Trimethoxybenzene selectively inhibits NLRP3 inflammasome activation and attenuates experimental autoimmune encephalomyelitis

Pan, RY; Kong, XX; Cheng, Y; Du, L; Wang, ZC; Yuan, C; Cheng, JB; Yuan, ZQ; Zhang, HY; Liao, YJ

Liao, YJ (corresponding author), Minzu Univ China, Coll Life & Environm Sci, Ctr Translat Neurosci, Beijing 100081, Peoples R China.; Liao, YJ (corresponding author), Beijing Inst Basic Med Sci, Brain Sci Ctr, Beijing 100850, Peoples R China.; Zhang, HY; Liao, YJ (corresponding author), Jiangxi Univ Tradit Chinese Med, Key Lab Modern Preparat TCM, Minist Educ, Nanchang 330004, Jiangxi, Peoples R China.; Liao, YJ (corresponding author), Hunan Prov Maternal & Child Hlth Care Hosp, NHC Key Lab Birt

ACTA PHARMACOLOGICA SINICA, ; ():

Abstract

NOD-like receptor (NLR) family pyrin domain-containing-3 (NLRP3) inflammasome is implicated in inflammation-associated diseases such as multiple scler......

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