AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis

Ma, CM; Li, S; Hu, YC; Ma, Y; Wu, YQ; Wu, CY; Liu, X; Wang, BW; Hu, G; Zhou, JW; Yang, S

Yang, S (corresponding author), Nanjing Med Univ, State Key Lab Reprod Med, Key Lab Immunol Environm & Dis, Dept Immunol,Ctr Global Hlth, Nanjing, Peoples R China.; Hu, G (corresponding author), Nanjing Univ Chinese Med, Dept Pharmacol, Nanjing, Peoples R China.; Zhou, JW (corresponding author), Chinese Acad Sci, Ctr Excellence Brain Sci & Intelligence Technol, State Key Lab Neurosci, Shanghai Inst Biol Sci,Inst Neurosci, Shanghai, Peoples R China.; Zhou, JW (corresponding author), Univ Chinese

JOURNAL OF EXPERIMENTAL MEDICINE, 2021; 218 (5):

Abstract

The role of the PYHIN family member absent in melanoma 2 (AIM2), another important inflammasome sensor, in EAE remains unclear. In this study, we foun......

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