Optimizing NK-92 serial killers: gamma irradiation, CD95/Fas-ligation, and NK or LAK attack limit cytotoxic efficacy

Navarrete-Galvan, L; Guglielmo, M; Amaya, JC; Smith-Gagen, J; Lombardi, VC; Merica, R; Hudig, D

Hudig, D (通讯作者),Univ Nevada, Reno Sch Med, Reno, NV 89557 USA.

JOURNAL OF TRANSLATIONAL MEDICINE, 2022; 20 (1):

Abstract

Background The NK cell line NK-92 and its genetically modified variants are receiving attention as immunotherapies to treat a range of malignancies. H......

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