High-Dose IL-2 Skews a Glucocorticoid-Driven IL-17(+)IL-10(+) Memory CD4(+) T Cell Response towards a Single IL-10-Producing Phenotype

Mann, EH; Gabrysova, L; Pfeffer, PE; O'Garra, A; Hawrylowicz, CM

Hawrylowicz, CM (reprint author), Kings Coll London, Guys Hosp, Sch Immunol & Microbial Sci, Asthma UK Ctr Allerg Mech Asthma,Peter Gorer Dept, 5th Floor,Tower Wing, London SE1 9RT, England.

JOURNAL OF IMMUNOLOGY, 2019; 202 (3): 684

Abstract

Glucocorticoids are known to increase production of the anti-inflammatory cytokine IL-10, and this action is associated with their clinical efficacy i......

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