Unidirectional transport of IgG by neonatal Fc receptor in human thyrocytes varies across different IgG subclasses

Zhao, CX; Gao, Y; Yu, N; Li, TC; Zhang, Y; Zhang, H; Lu, GZ; Gao, YM; Guo, XH

Zhang, Y (reprint author), Peking Univ, Hosp 1, Dept Endocrinol, 8 Xishiku St, Beijing 100034, Peoples R China.

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2018; 477 (): 103

Abstract

Neonatal Fc receptor (FcRn) is down-regulated in Hashimoto's thyroiditis (HT) thyrocytes and mediates IgG endocytosis in thyrocytes. The serum distrib......

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