ATF6 alpha promotes prostate cancer progression by enhancing PLA2G4A-mediated arachidonic acid metabolism and protecting tumor cells against ferroptosis

Zhao, R; Lv, Y; Feng, TT; Zhang, RJ; Ge, LN; Pan, JH; Han, B; Song, GH; Wang, L

Wang, L (通讯作者)，Shandong First Med Univ & Shandong Acad Med Sci, Biomed Sci Coll, Key Lab Biotech Drugs Natl Hlth Commiss, Key Lab Rare & Uncommon Dis Shandong Prov, 6699 Qingdao Rd, Jinan 250017, Peoples R China.;Wang, L (通讯作者)，Shandong First Med Univ & Shandong Acad Med Sci, Shandong Med Biotechnol Ctr, 6699 Qingdao Rd, Jinan 250017, Peoples R China.;Song, GH (通讯作者)，Shandong First Med Univ & Shandong Acad Med Sci, Inst Basic Med, 6699 Qingdao Rd, Jinan 250017, Peoples R China.

PROSTATE, 2022; 82 (5): 617

Abstract

Background: Despite the clinical success of androgen receptor (AR)-targeted therapies, prostate cancer (PCa) inevitably progresses to castration-resis......

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