Asparagine and Glutamine Residues Participate in Protein Covalent Binding by Epoxide Metabolite of 8-Epidiosbulbin E Acetate In Vitro and In Vivo

Zhang, N; Yang, Y; Li, W; Zhou, SZ; Li, WW; Peng, Y; Zheng, J

Peng, Y; Zheng, J (通讯作者)，Shenyang Pharmaceut Univ, Wuya Coll Innovat, Shenyang 110016, Liaoning, Peoples R China.;Li, WW; Zheng, J (通讯作者)，Guizhou Med Univ, State Key Lab Funct & Applicat Med Plants, Key Lab Pharmaceut Guizhou Prov, Guiyang 550025, Guizhou, Peoples R China.

CHEMICAL RESEARCH IN TOXICOLOGY, 2022; 35 (10): 1821

Abstract

Dioscorea Bulbifera L. (DBL), an effective traditional Chinese medicine, has been restricted because of multiple reports that it can cause severe hepa......

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