TXNIP aggravates cardiac fibrosis and dysfunction after myocardial infarction in mice by enhancing the TGFB1/Smad3 pathway and promoting NLRP3 inflammasome activation

Zhang, Y; Wang, J; Wang, XJ; Li, AY; Lei, ZD; Li, DX; Xing, DH; Zhang, YC; Su, WZ; Jiao, XY

Jiao, XY (通讯作者)，Shanxi Med Univ, Minist Educ, Key Lab Cellular Physiol, Shanxi Med Univ, Taiyuan 030001, Peoples R China.;Jiao, XY (通讯作者)，Shanxi Med Univ, Dept Physiol, Taiyuan 030001, Peoples R China.

ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023; 55 (12): 1950

Abstract

Myocardial infarction (MI) results in high mortality. The size of fibrotic scar tissue following MI is an independent predictor of MI outcomes. Thiore......

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