Renal transporter OAT1 and PPAR-α pathway co-contribute to icaritin-induced nephrotoxicity

Wang, DL; Liu, J; Chen, XD; Chen, J; Zhao, TT; Du, J; Wang, CY; Meng, Q; Sun, HJ; Wang, FJ; Liu, KX; Wu, JJ

Wu, JJ (通讯作者)，Dalian Med Univ, Coll Pharm, Dalian 116044, Peoples R China.;Wang, FJ (通讯作者)，Chinese Acad Sci, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China.

PHYTOTHERAPY RESEARCH, 2023; 37 (2): 549

Abstract

This study aimed to investigate the potential nephrotoxicity of icaritin arid the underlying mechanism by in vitro-in vivo experiment technology combi......

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