Phosphorylation of Ser82 on IRF3 acts as negative-feedback regulation of IRF3-dependent innate immunity

Cheng, Q; Yuan, LJ; Guo, JH; Guo, DY; Liu, XY; Li, S

Liu, XY (通讯作者)，Jinan Univ, Dept Crit Care Med, Shenzhen Peoples Hosp, Affiliated Hosp 1,Southern Univ Sci & Technol,Clin, Shenzhen, Peoples R China.;Li, S (通讯作者)，Chinese Acad Sci, CAS Key Lab Quantitat Engn Biol, Shenzhen Inst Synthet Biol, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2022; 150 ():

Abstract

Interferon Regulatory Factor 3 (IRF3) is essential for the production of type I interferon (IFN) during virus infection; however, the mechanism underl......

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