Dual modes of CRISPR-associated transposon homing

Saito, M; Ladha, A; Strecker, J; Faure, G; Neumann, E; Altae-Tran, H; Macrae, RK; Zhang, F

Zhang, F (corresponding author), Howard Hughes Med Inst, Cambridge, MA 02139 USA.; Zhang, F (corresponding author), Broad Inst MIT & Harvard, Cambridge, MA 02142 USA.; Zhang, F (corresponding author), MIT, McGovern Inst Brain Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA.; Zhang, F (corresponding author), MIT, Dept Brain & Cognit Sci, 77 Massachusetts Ave, Cambridge, MA 02139 USA.; Zhang, F (corresponding author), MIT, Dept Biol Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA.

CELL, 2021; 184 (9): 2441

Abstract

Tn7-like transposons have co-opted CRISPR systems, including class 1 type I-F, I-B, and class 2 type V-K. Intriguingly, although these CRISPR-associat......

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