The non-steroidal mineralocorticoid receptor antagonist finerenone prevents cardiac fibrotic remodeling

Lavall, D; Jacobs, N; Mahfoud, F; Kolkhof, P; Bohm, M; Laufs, U

Lavall, D (reprint author), Univ Klinikum Leipzig, Klin & Poliklin Kardiol, Liebigstr 20, D-04103 Leipzig, Germany.

BIOCHEMICAL PHARMACOLOGY, 2019; 168 (): 173

Abstract

Mineralocorticoid receptor (MR) overactivation promotes cardiac fibrosis. We studied the ability of the non-steroidal MR antagonist finerenone to prev......

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