First-in-human phase I/II, open-label study of the anti-OX40 agonist INCAGN01949 in patients with advanced solid tumors

Davis, EJ; Martin-Liberal, J; Kristeleit, R; Cho, DC; Blagden, SP; Berthold, D; Cardin, DB; Vieito, M; Miller, RE; Dass, PH; Orcurto, A; Spencer, K; Janik, JE; Clark, J; Condamine, T; Pulini, J; Chen, XJ; Mehnert, JM

Mehnert, JM (通讯作者),Rutgers State Univ, New Brunswick, NJ 08901 USA.

JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022; 10 (10):

Abstract

Background OX40 is a costimulatory receptor upregulated on antigen-activated T cells and constitutively expressed on regulatory T cells (Tregs). INCAG......

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